Longevity, senescence, and the genome / Caleb E. Finch
- Bib ID:
- 316807
- Format:
- Book
- Author:
- Finch, Caleb Ellicott
- Online Version:
- Table of contents only
Broken link? let us search Trove , the Wayback Machine , or Google for you.
- Related Online Resources:
- Publisher description
Broken link? let us search Trove , the Wayback Machine , or Google for you.
- Description:
-
- Chicago : University of Chicago Press, 1990
- xv, 922 p. : ill. ; 25 cm.
- ISBN:
- 0226248887
- Series:
- John D. and Catherine T. MacArthur Foundation series on mental health and development.
- Full contents:
-
- Machine derived contents note: Preface
- Synopsis
- Section I. The Comparative Biology of Senescence
- 1. Introduction
- 1.1 The Agenda
- 1.2 Definitions and Concepts
- 1.3 Sources of Information and Experimental Approaches
- 1.4 Mortality Rates and Lifespans
- 1.5 Evolution and the Relationships between Reproduction and Senescence
- 1.6 Summary
- 2 Rapid Senescence and Sudden Death
- 2.1 Introduction
- 2.2 Developmental Determinants of Rapid Senescence
- 2.3 Reproduction-related Rapid Senescence and Sudden Death
- 3. Gradual Senescence with Definite Lifespan
- 3.1 Introduction
- 3.2 Clonal Senescence in Ciliates
- 3.3 Plants and Invertebrates
- 3.4 Fish and Lower Vertebrates
- 3.5 Birds
- 3.6 Mammals
- 3.7 Summary
- 4. Negligible Senescence
- 4.1 Introduction
- 4.2 Indeterminante Lifespans and Negligible Senescence
- 4.3 Finite Lifespans with Negligible Senescence
- 4.4 Vegetative Reproduction by Somatic Cell Cloning
- 4.5 Summary of Chapters 2-4
- 5. Rates of Living and Dying: Correlations of Lifespan with Size, Metabolic Rates, and Cellular and Biochemical Characteristics
- 5.1 Introduction
- 5.2 Correlations of Body Size and Metabolic Rates
- 5.3 Lifespan, Size, and Metabolism
- 5.4 Cellular and Biochemical Correlations with Lifespan
- 5.5 Summary
- 6. Genetic Influences on Lifespan, Mortality Rates, and Age-related Diseases
- 6.1 Introduction
- 6.2 The Nematode Caenorhabditis
- 6.3 Insects
- 6.4 Fungi and Plants
- 6.5 Mammals
- 6.6 Summary
- Section II. Genomic Functions during Senescence
- 7. Gene Expression and Macromolecular Biosynthesis
- 7.1 Introduction
- 7.2 Caveats and Perspectives
- 7.3 Differential Gene Expression
- 7.4 RNA and Protein Synthesis
- 7.5 Post-translational Modifications
- 7.6 Cell Proliferation and DNA Synthesis
- 7.7 Cell Death
- 7.8 Memories and Gene Expression
- 7.9 Summary
- 8. Fidelity and Maintenance of Genomic DNA and Its Replication during Senescence
- 8.1 Introduction
- 8.2 Somatic Cells and Age-related Modifications of Genetic Structure
- 8.3 Cancer and Age-related Genetic Changes
- 8.4 Plasmids and Episomes in Somatic Cells
- 8.5 Parental Age and Abnormalities in Gametogenesis, Fertility, and Development
- 8.6 Summary
- 9. Developmental Influences on Lifespan and Senescence
- 9.1 Introduction
- 9.2 Influences on Total Lifespan through Variable Durations of Developmental Stages
- 9.3 Developmental Influences on Patterns of Senescence
- 9.4 Developmental Determinants of Regeneration and Cell Renewal
- 9.5 Summary
- 10. Postmaturational Influences on the Phenotypes of Senescence
- 10.1 Introduction
- 10.2 Ambient Temperature and Lifespan
- 10.3 Diet and Caloric Restriction
- 10.4 Sex Hormones
- 10.5 Stress and Corticosteroids
- 10.6 Costs of Reproduction and Accelerated Senescence
- 10.7 Immunological Changes and Hormones
- 10.8 Hypophysectomy
- 10.9 The Biomarker Problem: How to Measure Influences on Senescence
- 10.10 Summary
- 11. Phylogeny and Evolutionary Changes in Longevity and Senescence
- 11.1 Introduction
- 11.2 An Outline of Evolution and a Discussion of Early Biochemical and Molecular Changes
- 11.3 Examples of Phylogenetic Variations in Senescence and Longevity
- 11.4 Factors in the Evolution of Senescence and Longevity
- 11.5 Summary
- 12. Genome Mechanisms in the Biology of Extended Time
- 12.1 Introduction
- 12.2 The Agenda Revisited
- 12.3 Exogenous Factors, Endogenous Factors, and Cascades
- 12.4 Types of Genetic Influence on the Lifespan
- 12.5 Aging in the Biology of Extended Time
- Appendix 1
- Appendix 2
- Appendix 3
- Glossary
- Bibliography
- Author Index
- Species Index
- Subject Index.
- Notes:
- Includes bibliographical references (p. [681]-843) and indexes.
- Subject:
- Copyright:
-
In Copyright
You may copy under some circumstances, for example you may copy a portion for research or study. Order a copy through Copies Direct to the extent allowed under fair dealing. Contact us for further information about copying.
Copyright status was determined using the following information:
- Material type:
- Literary Dramatic Musical
- Published status:
- Published
- Publication date:
- 1990
Copyright status may not be correct if data in the record is incomplete or inaccurate. Other access conditions may also apply. For more information please see: Copyright in library collections.
Request this item
Request this item to view in the Library’s reading room.
Loading...
Feedback
Similar items
- Chang shou zhi dao / Chen Dezhi ... [et al.]
- The prolongation of life, by Alexander A. Bogomolets. Translated by Peter V. Karpovich, M.D., and Sonia Bleeker
- Er bai wu shi sui ren rui shi ji / Yang Sen deng zhu
- An essay on longevity [microform] / by John Sinclair
- An essay on longevity [electronic resource] / by John Sinclair